Theraflex macopharma

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August undefined, 2024

WebbBackground: The THERAFLEX UV-Platelets system uses shortwave ultraviolet C light (UVC, 254 nm) to inactivate pathogens in platelet components. Plasma carryover influences … WebbStefan Reichenberg currently works at the Medical Department of Macopharma. Stefan does research in Virology, Molecular Biology and Microbiology. Their current project is …

Towards pathogen inactivation of red blood cells and whole blood ...

WebbPathogen inactivation technologies represent a shift in blood safety from a reactive approach to a proactive protective strategy. Commercially available technologies demonstrate effective killing of most viruses, bacteria, and parasites and are capable of inactivating passenger leukocytes in blood products. The use of pathogen inactivation … Webb1 aug. 2024 · PCs were subjected to UV-C treatment using dedicated illumination devices (kit XUV4005XU and Macotronic UV illumination machine, Macopharma), in accordance with the THERAFLEX UV-Platelets procedure. A standard illumination dose of 0.2 J/cm 2 was used under agitation of the bag, as recommended by the manufacturer. hilfe postfinance

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WebbAbout Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features Press Copyright Contact us Creators ... Webb1 apr. 2012 · The THERAFLEX UV-Platelets system is based on application of the well-established sterilisation capability of monochromatic UVC light at a wavelength of 254 nm, which coincides closely with the maximum absorption of DNA/RNA (260 nm range) and where plasma protein absorption is at its minimal value [17] (Fig. 1).Short-wave UV light … WebbTraductions en contexte de "termes de commodité, sécurité et efficacité" en français-anglais avec Reverso Context : Ces systèmes présentent des limitations majeures en termes de commodité, sécurité et efficacité. hilfe psychologie notfalltelefon

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MacoTronic B2 illumination machine - Macopharma

WebbTHERAFLEX UV Platelets Trial Name/ Study Location Study Type Study Design N Reference Cambridge, UK Recovery and Survival Open, controlled radiolabeled autologous UV buffy … WebbLe système THERAFLEX UV-Platelets est destiné à inactiver un large spectre d’agents pathogènes ainsi que les leucocytes résiduels des donneurs dans les concentrés … smarsh annual reportWebbConclusions: Our study demonstrates that the THERAFLEX UV-Platelets system and THERAFLEX MB-Plasma system can reduce ZIKV infectivity in PCs and pooled plasma to the detection limit of the assays used. These findings suggest both systems have the capacity to be an effective option to manage potential ZIKV transfusion transmission … hilfe prostata

"Webb1 feb. 2015 · Theraflex UVC-based pathogen reduction treatment (MacoPharma, Mouvaux, France) The Theraflex UVC treatment uses exposure to short wavelength monochromatic UVC light (254 nm) that has a unique ability to interfere with DNA/RNA replication while preserving protein integrity, exploiting the maximum absorption capacity of DNAs or … " - Theraflex macopharma

Theraflex macopharma

Inactivation of three emerging viruses - severe acute respiratory ...

Webb23 jan. 2024 · THERAFLEX (MacoPharma, Mouveux, France). All three dem-onstrate clinically signiﬁcant reduction of bacteria in platelets 3, 4. Recent reviews by Gravemann, Y onemura, and Schubert . Webb20 mars 2024 · The present project is a prospective, multicenter, non-randomized, phase II trial which aims to evaluate the clinical impact and the safety of extracorporeal photopheresis (ECP) using the Theraflex system in patients with refractory chronic graft versus host disease (cGVHD) after any type of hematopoietic stem cell transplantation …

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WebbThe THERAFLEX UV-Platelets (Macopharma, Mouvaux, France) method for pathogen reduction (PR) of platelet products is based on treatment with UVC light alone, without … WebbAn approach to manage the potential YFV transfusion transmission risk is the use of pathogen inactivation (PI) technology systems, such as THERAFLEX MB-Plasma and THERAFLEX UV-Platelets (Macopharma). We aimed to investigate the efficacy of these PI technology systems to inactivate YFV in plasma or platelet concentrates (PCs).

WebbConclusions: The THERAFLEX MB-Plasma and THERAFLEX UV-Platelets systems effectively inactivated JEV in plasma or PCs, and thus these PI technologies could be an effective option to reduce the risk of JEV transfusion transmission.

Webb4 maj 2024 · Current pathogen reduction technologies use nucleic acid–binding compounds either alone, such as S‐303, or nucleic acid–binding compounds in conjunction with ultraviolet (UV) light, such as amotosalen used with UV‐A (INTERCEPT, Cerus Corporation) or riboflavin used with UV‐A and UV‐B (MIRASOL, Terumo BCT), or use … WebbMacopharma 1977 First affiliate in Germany 1995 New ISO 9001 production site in Poland 2002 20th February 2024 Research on pathogen reduction with methylene blue on …

WebbTHERAFLEX MB-Plasma disposable set A user-friendly and effective pathogen inactivation technique against enveloped and non-enveloped viruses designed for single units of …

WebbThe THERAFLEX UV-Platelets (Macopharma, Mouvaux, France) method for pathogen reduction (PR) of platelet products is based on treatment with UVC light alone, without any photoactive substances. 6 UVC is absorbed by nucleic acids, resulting in the formation of pyrimidine dimers, which block the elongation of nucleic acid transcripts. hilfe programmWebb17 apr. 2024 · Specifically, the fully integrated Therakos CELLEX®system was used, and the multi‐step procedures included cell separation using Spectra Optia®, and UVA irradiation using MacoPharma®Theraflex MB‐Plasma. Informed, written consent was obtained from both patients prior to the procedures. hilfe psychoseWebbThe MacoTronic B2: the newest generation of illumination device for THERAFLEX MB-Plasma FAST • Short illumination cycle (~ 15 min.) due to optimal wavelength (627 +/- … smarsh apiWebb17 juli 2024 · The THERAFLEX UV-Platelets system, designed by MacoPharma for plasma-reduced platelets (PLTs) in additive solution (PAS), utilizes ultraviolet C (UVC) light with agitation to cause cyclobutane-pyrimidine and pyrimidine-pyrimidone dimers within the genome of the pathogen, thus preventing elongation of the nucleic acid transcripts. 19 … hilfe redmedicalWebbsolution (Macopharma, Mouvaux, France) and prepared according to French transfusion practices were obtained from EFS Nord de France. PCs were subjected to UV-C treatment using dedicated illumination devices (kit XUV4005XU and Macotronic UV illumination machine, Macopharma), in accordance with the THERAFLEX UV-Platelets procedure. A smarsh annual revenueWebbSusanne Marschner PhD, Raymond P. Goodrich PhD, in Transfusion Medicine and Hemostasis (Second Edition), 2013. Methylene-Blue. Methylene-blue, a photoactive phenothiazine dye, when added to plasma and exposed to visible light, can inactivate enveloped viruses in single units of plasma and has been used in Europe for … hilfe pecsWebbA Biblioteca Virtual em Saúde é uma colecao de fontes de informacao científica e técnica em saúde organizada e armazenada em formato eletrônico nos países da Região Latino-Americana e do Caribe, acessíveis de forma universal na Internet de modo compatível com as bases internacionais. hilfe psychologisch