List of platinum based chemotherapy agents
WebThe two platinum agents most commonly used for treating metastatic breast cancer are carboplatin and cisplatin. The original version of this review (2004) concluded that … Web8 nov. 2024 · Among the 2415 TNBC patients who underwent platinum-based neoadjuvant chemotherapy, this study showed statistically significant improvement in pCR rates compared to non-platinum-based treatment. However, this data is affected by moderate heterogeneity among the studies, which has been associated with the varied agents …
List of platinum based chemotherapy agents
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Web1 apr. 2024 · Platinum-based chemotherapy regimens have been proven to be effective in various cancers; however, considerable toxicities may develop and can even lead to treatment discontinuation. Diverse factors may influence adverse treatment events, with pharmacogenetic variations being one prime example. Polymorphisms within the … WebComparison of single agent versus combined chemotherapy in previously treated patients with advanced urothelial carcinoma: a meta-analysis Xiao-Jun Wu, Yi Zhi, Peng He, Xiao …
Web1 aug. 2007 · Key developments include the elucidation of mechanisms of tumour resistance to these drugs, the introduction of new platinum-based agents (oxaliplatin, satraplatin and picoplatin), and clinical combination studies using platinum drugs with resistance modulators or new molecularly targeted drugs. The accidental discovery of the … Web14 apr. 2024 · Doctors use platinum drugs to treat many kinds of cancer, both alone and in combination with other drugs. Cisplatin, the oldest, has been approved as a cancer treatment since 1978. In the U.S.,...
Web16 mrt. 2024 · We read with great interest the letter by Poggio et al.,1 updating their previous meta-analysis on the role of platinum compounds in neoadjuvant chemotherapy (NAC) of triple-negative breast cancer (TNBC).2 The current results indicate that adding a platinum agent significantly increases event-free survival (EFS) but not overall survival … Web22 apr. 2024 · that they might be more sensitive to platinum damage. Based on this biological rationale, several studies have evaluated the impact of adding platinum-based agents to standard chemotherapy; however, the results are con-flicting.8–10 Meanwhile, current recommenda-tions in several international breast cancer guidelines are also …
WebPlatinum agents are used to treat lymphomas, sarcomas, breast, colorectal, germ cell, ovarian, lung, gastro-oesophageal and bladder cancers. Most retrospective data …
Web20 jul. 2024 · Platinum-based chemotherapy with cisplatin (the prototype of platinum agents) and its derivatives, carboplatin and oxaliplatin, is traditionally the first-line cytotoxic treatment of lung, colorectal, ovarian, breast, head/neck, bladder and testicular cancers [].An expected side effect of these widely administered platinum-containing regimens is … daiwa plasticsWebNSCLC is the leading cause of cancer-related death in the US. Patients with NSCLC are mostly treated with platinum-based chemotherapy, often in combination with radiation … biotechnology laboratory sciences valenciaWeb1 jul. 2001 · Cisplatin (Platinol) isone of the most active drugs in non-small-cell lung cancer (NSCLC), with asingle-agent response rate of approximately 20%. In many different preclinicalmodels, platinum is synergistic with other chemotherapy drugs and withradiation. The superiority of platinum-containing chemotherapy was suggested bya … biotechnology laboratory specialist salaryWeb21 sep. 2016 · Randomized phase II and III clinical trials comparing first-line palliative platinum-based chemotherapy with the same regimen without platinum or with platinum replaced by a nonplatinum agent were identified by electronic searches of Medline, Embase, and Cancerlit, and hand searches of relevant abstract books and reference lists. daiwa pier39 tech loose stretch 6p mil pantsWeboxaliplatin as low as $68 OXALIPLATIN is a chemotherapy drug. It targets fast dividing cells, like cancer cells, and causes these cells to die. This medicine is used to treat … biotechnology laboratory sciences salarybiotechnology laboratory specialistWeb13 apr. 2024 · Eighty-nine percent of patients previously received androgen-signaling inhibitor(s), 68% had platinum-based chemotherapy, and 50% had prior taxane chemotherapy. The median duration of follow-up was 30.8 weeks (range, 1.9-86.9), and the median duration of treatment was 9 weeks (range, 0.7-63). daiwa plastics thang long co. ltd