High steacs trial

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WebAug 1, 2024 · The High-STEACS trial (High-Sensitivity Troponin in the Evaluation of Patients With Suspected Acute Coronary Syndrome) 7 assessed whether implementing high-sensitivity cardiac troponin testing and the recommendations of the Universal Definition of Myocardial Infarction led to changes in investigation, treatment, and outcomes in patients … WebDec 19, 2015 · This trial is registered with ClinicalTrials.gov (number NCT01852123). Findings: In patients without myocardial infarction at presentation, troponin concentrations were less than 5 ng/L in 2311 (61%) of 3799 patients, with a negative predictive value of 99·6% (95% CI 99·3-99·8) for the primary outcome.

Hs-TnI in Suspected ACS: High-STEACS Trial - American

WebTrial Start Date: 10 June 2013 Trial Finish Date: 02 March 2024 Trial Report Date: 02 September 2024 Correspondence Address and Main Centre: Professor Nicholas L Mills Room SU225, Chancellor's Building, University of Edinburgh, Royal Infirmary, Little France, Edinburgh, EH16 4SB, UK. WebA high-sensitivity troponin assay (hs-TnI) (ARCHITECT stat; Abbott Laboratories, USA) was used to guide clinical decisions This particular assay has a 99th centile upper reference limit of 34 ng/L in men and 16 … the race nick harlow

First randomised trial tests criteria used to EurekAlert!

WebAug 18, 2014 · A high-stakes test is any test used to make important decisions about students, educators, schools, or districts, most commonly for the purpose of … WebOct 14, 2024 · The High-STEACS trial presented an opportunity to explore whether improved diagnostic testing—by transitioning from a conventional to a high-sensitivity cardiac troponin I test, using sex-specific thresholds, and applying the recommendations of the universal definition of MI—had differential impacts on the evaluation, treatment, and outcomes of … WebMar 14, 2024 · When the outcome of a standardized test is used as the sole determining factor for making a major decision, it is known as high-stakes testing. Common examples … sign off email with look forward to

High-sensitivity Troponin in the Evaluation of patients …

High-Sensitivity Cardiac Troponin and the Universal

WebSep 20, 2024 · The High-STEACS trial adopted a stepped-wedge, cluster-randomization of 10 hospitals in Scotland, and consisted of 2 phases: a validation phase of 6 months … WebAug 28, 2024 · The High-STEACS trial makes use of several routine electronic health care data sources that are linked, de-identified, and held in our national safe haven, which is … theracentric appWebThe aim of this trial was to find out whether heart attack survival rates could be improved by using a new high-sensitivity troponin test to make the diagnosis. What did the study … sign off examples for letters

"WebThe High-STEACS trial makes use of several routine electronic health-care data sources that are linked, de-identified, and held in DataLoch Safe Haven, which is accessible by approved individuals who have undertaken the necessary governance training. Summary aggregate level data and analysis code for this study can be made available upon ... " - High steacs trial

High steacs trial

High-Sensitivity Troponin Does Not Improve MI Outcomes - Medscape

WebAug 28, 2024 · The High-STEACS trial 5 is the first randomised trial to evaluate whether the introduction of a high-sensitivity cardiac troponin I assay with a 99th centile diagnostic threshold would reduce subsequent myocardial infarction or cardiovascular death at one year in patients with suspected acute coronary syndrome. WebHigh-STEACS Trial Protocol Version 7.0 16/05/2024 High-sensitivity Troponin in the Evaluation of patients with Acute Coronary Syndrome ( HighSTEACS): A randomised …

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WebJun 25, 2024 · High-STEACS is a stepped-wedge cluster randomized controlled trial that evaluated the implementation of a high-sensitivity cardiac troponin I assay in consecutive patients with suspected acute … WebAug 4, 2016 · The ongoing High-Sensitivity Troponin in the Evaluation of Patients with Acute Coronary Syndrome (High-STEACS) trial 31 is investigating the clinical implications of a high-sensitivity...

WebMay 13, 2013 · In ten secondary and tertiary care hospitals across Scotland, the investigators will undertake a stepped wedge cluster randomized controlled trial of the … WebApr 1, 2024 · This large multicenter trial of close to 31,500 patients from seven centers in Scotland confirms dramatic benefits of adopting an early rule-out strategy, with a 3.3-hour reduction in length of stay in the ED and a 59% decrease in hospital admission, without impacting safety.

WebOct 7, 2024 · High-STEACS (High-Sensitivity Troponin in the Evaluation of Patients With Suspected Acute Coronary Syndrome) is a stepped-wedge cluster randomized, controlled … WebAug 28, 2024 · High-STEACS was conducted at ten Scottish hospitals where 48,282 consecutive patients (61 years old on average, 47% women) arrived at the emergency department with suspected ACS. Individuals...

WebJan 14, 2016 · The High-STEACS trial investigators conducted a prospective cohort study of 6,304 consecutively enrolled patients with suspected acute coronary syndrome presenting to four secondary and tertiary care hospitals in Scotland. They measured plasma troponin concentrations at presentation using a high-sensitivity cardiac troponin I assay.

WebDec 10, 2024 · study of the High-STEACS trial (High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome). All patients in whom the attending clinician requested car-diac troponin for suspected acute coronary syndrome were eligible for inclusion. We did not enroll patients with ST-segment–elevation myocardial infarction, … sign offers latestWebOct 15, 2024 · This study is a prespecified secondary analysis of the High-STEACS (High-Sensitivity Troponin in the Evaluation of Patients With Suspected Acute Coronary Syndrome) trial, which evaluated the impact of incorporating hs-TnI in the evaluation of patients suspected of ACS on outcomes. A total of 48,282 consecutive patients (47% women) with ... the race mythWebNov 22, 2024 · We assessed the accuracy and clinical effectiveness of high-sensitivity cardiac troponin (hs-cTn) assays for early rule-out of non-ST-segment elevation myocardial infarction (NSTEMI) in adults presenting with acute chest pain. Methods Sixteen databases were searched to September 2024. Review methods followed published guidelines. sign off electrical workWebJul 11, 2024 · Trial Protocol and Statistical Analysis Plan Supplement 2. eMethods. eTable 1. Characteristics of the Study Population According to Adjudicated Diagnosis (Type 1 … sign of feet and inchWebIn the High-STEACS trial,99during the validation phase of the trial (6–12 months), results of the hs-cTnI assay were concealed from the attending clinician and a contemporary cTn assay was used to guide care. sign off favored by stan lee crosswordWebNov 7, 2024 · Biological Science Troponin Diagnosing myocardial infarction in the era of high-sensitivity troponin: the High-STEACS trial Cardiovascular Research License CC BY 4.0 Authors: Atul Anand... sign off document คือWebAug 29, 2024 · When the STEACS Are High The study enrolled more than 48,000 consecutive patients presenting with chest pain to one of 10 Scottish hospitals, with all patients … sign offers exclusive