Des-γ-carboxy-prothrombin
WebDes-γ-Carboxy Prothrombin. Serum concentrations of des-γ-carboxy prothrombin (DCP) (also known as prothrombin produced by vitamin K absence or antagonist II) are raised in most patients with HCC. 65 DCP is an abnormal prothrombin that is thought to result from a defect in the post-translational carboxylation of the prothrombin precursor … WebNov 20, 2024 · A des-gamma-carboxy prothrombin (DCP) test may be used along with other tumor markers such as an alpha ... Bertino N, Boemi PM. 2010. Prognostic and …
Des-γ-carboxy-prothrombin
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WebDes-gamma-carboxy prothrombin (DCP), also known as PIVKA-II, is a form of factor II produced in the absence of vitamin K, and is therefore an unmodified form of the protein. … WebApr 12, 2016 · Des-γ-carboxy prothrombin (DCP), also known as the protein induced by vitamin K deficiency or antagonist-II (PIVKA-II), was first reported in 1984 . Several studies have demonstrated that DCP is a useful marker for HCC, and higher DCP levels indicated worse clinical features of HCC [10,11,12].
WebNov 29, 2015 · Determining the serum des-γ-carboxy-prothrombin (DCP) level is of great importance for the diagnosis of primary hepatocellular carcinoma (PHC). Although several studies have investigated the accuracy of diagnostic DCP tests for PHC, the results have been inconsistent. The aim of this study was to systematically evaluate DCP as a … WebDes-γ-carboxy prothrombin (DCP), also referred to as protein induced by vitamin K absence (PIVKA-II), is a nonfunctional precursor of prothrombin. 7 Prothrombin, …
Des-gamma carboxyprothrombin (DCP), also known as protein induced by vitamin K absence/antagonist-II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin. Normally, the prothrombin precursor undergoes post-translational carboxylation (addition of a carboxylic acid group) by gamma-glutamyl carboxylase in the liver prior to secretion into plasma. DCP/PIVKA-II may be detected in people with deficiency of vitamin K (due to poor nutrition or mal…
WebProtein induced by vitamin K or antagonist-II (PIVKA-II; also known as des-γ-carboxy prothrombin [DCP]) has been identified as a promising biomarker with utility in the surveillance, diagnosis, and management of …
WebFeb 12, 2024 · Background: The role of des-γ-carboxy prothrombin (DCP) in patients undergoing radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) needs to be clarified. Materials and methods: 174 ... dickies school uniforms for juniorsWebDes-γ-carboxy (abnormal) prothrombin and hepatocellular carcinoma: A critical review. Ilene C. Weitz, Ilene C. Weitz. Division of Hematology and Oncology, Department of Medicine, Sepulveda Veterans Administration Hospital-San Fernando Valley Medical Center and the UCLA School of Medicine, Los Angeles. dickies school uniform pants boysWebWe detected des-γ-carboxy prothrombin, an abnormal prothrombin, in the serum of 69 of 76 patients (91 per cent) with biopsy-confirmed hepatocellular carcinoma (the mean level of the abnormal ... dickies school uniforms walmartWebNov 20, 2000 · Des-γ-carboxy prothrombin (DCP) is an established marker for hepatocellular carcinoma (HCC), but the conventional enzyme immunoassay (EIA) kit lacks adequate sensitivity. Thus, a revised EIA kit with increased sensitivity has been developed. In this kit, the sensitivity has increased while high specificity to HCC has been maintained. dickies scrub hatsWebNov 1, 1991 · Abnormal (des-γ-carboxy) prothrombin, defined as a protein induced by vitamin K absence or antagonist-II (PIVKA-II) was measured in the cases with hepatocellular carcinoma by a newly developed ... dickies school uniforms for girlsWebDes-gamma-carboxy prothrombin (DCP), also known as the protein induced by vitamin K absence or antagonist II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin. DCP is a nonfunctional prothrombin resulting from a lack of carboxylation … dickies school uniform shirtsWebIt remains unclear whether hepatocellular carcinoma (HCC) recurrence in hepatitis C virus (HCV)-infected patients can be suppressed by the elimination of the virus using direct-acting antivirals (DAAs) after radical HCC treatment. We evaluated the sustained inhibitory effect of DAAs on HCC recurrence after curative treatment. This multicenter retrospective study … dickies scooters